Juno MacGuff is a sixteen year-old who after a one-time sexual encounter with her best friend Paulie, learns that she's pregnant. Juno and Paulie like each other, but not enough to start a family, complete with a child. Paulie leaves all the decisions about the baby to Juno. Initially she decides to have an abortion, but can't go through with it. So she decides to have the baby and give it up for adoption. The next step is to find prospective parents...

Jenna is unhappily married. She squirrels away money and is hoping to win a pie-baking contest so, with the prize money, she'll have enough cash to leave her husband Earl. She finds herself pregnant and her plans are thrown awry. She bakes phenomenal pies at Joe's diner, listens to old Joe's wisdom, tolerates her sour boss Cal, is friends with her fellow waitresses, Dawn and Becky. She also finds a mutual attraction with the new doctor in town. Life...

As Amy's due date approaches, her secret marriage to Ben complicates matters even further. Amy will have to decide how to continue her life as a teenager, have the baby and then carry on life as she wants. Watch as their relationship twists and turns, and discover what the future holds for Ricky, Jack and the rest of the gang.

It's a whole new school year as Amy tries to juggle motherhood, school, work, and family, and Grace and Jack take their relationship to the next level.