The zombies are disappearing. This might seem like a good thing, since zombies eat your brains, but normal human kid Jack Sullivan is suspicious. He keeps hearing an eerie shrieking noise that seems to be almost summoning the zombiesbut to where, and for what (probably) foul purpose?

During the first winter after the Monster Apocalypse, Jack and his buddies prepare for a monstrous Christmas celebration, but a supervillainess steals Jack's prized monster-slaying weapon, his Louisville Slicer, and he vows to get it back.

While the kids plan their next move, an unexpected threat emerges and June gets separated from her friends, dragged miles away from Wakefield to a town overgrown with monstrous vines and never-before-seen creatures. Drawing on her post-apocalyptic survival and action skills--and with the help of some odd new companions--June attempts to make her way back home. But not before she uncovers critical information about the mysterious "Tower." Information...

"With his zombie-controlling powers growing stronger, Jack Sullivan and his buddies are road-tripping toward the mysterious Tower, where they must once and for all stop Rezzoch the Ancient, Destructor of Worlds, from descending upon our dimension. But their journey is sidetracked when they are swept up by the Mallusk, an enormous centipede monster carrying the world's largest shopping mall on its back. On board, the kids discover a thriving monster...

Picking up after Quint and Dirk's Hero Quest, the Last Kids are happily reunited--but quickly faced with a monstrous new mission. Inside an other-dimensional fortress, the evil Thrull, alongside a vile new villain, is carrying out a sinister plan. Jack, Quint, June and Dirk must make their own plans to infiltrate the stronghold before Thrull gets any closer to completing the mysterious Tower, a structure that could ultimately spell doom for this dimension....

"The last kids may have escaped the forbidden fortress by the skin of their teeth, but there isn't much to celebrate. Thrull has what he needs to complete the Tower, Rezzoch will most certainly come to Earth, and the world as they know it will cease to exist. Except Jack's Cosmic Hand is now even more powerful than he realized, and it might just be able to stop the inevitable from happening. To get the answers he seeks, he'll need to travel farther...